| Fabrication and mechanical properties of PLLA and CPC composite scaf-folds
Shanglong Xu*, Wei Guo, Junjun Lu and Wei Li
The Journal of Mechanical Science and Technology, vol. 26, no. 9, pp.2857-2862, 2012
Abstract : The brittleness and insufficient strength of biomaterials such as calcium phosphate cement (CPC) limit their applications in physiologically
non-load-bearing bone lesions. These limitations stimulated the research for developing degradable polymer-ceramic composite
materials that can closely match the modulus of bones. In this study, poly (L-lactic acid)/calcium phosphate cement (PLLA/CPC) composite
scaffolds were fabricated via a four-step process, namely, measurement, prototyping, compounding, and dissolving. The design
and mechanical properties of the PLLA/CPC composite structures were theoretically and experimentally studied. The PLLA/CPC scaffold
improved the mechanical properties of the CPC. The CPC’s compressive strength and strengthening percentage increase with higher
PLLA volume. Such composites may have a clinical use for load-bearing bone fixation.
Keyword : Mechanical properties; Fabrication; PLLA/CPC scaffold |
